Author(s) : Allan Siegel and Steven S. Zalcman Publisher : Springer Date       : 2008 Pages     : 438 Format    : PDF ISBN-10  : 0387848509

The fields of neuroscience, neuroimmunology, and psychiatry have seen remarkable growth over the past decade. For many years, it was believed that viruses, bacteria and other pathogens could precipitate psychiatric and neurological abnormalities. Recent developments in the field of neuroimmunology have provided insights into the possible relationships between immune function and behavioral disorders.

Specifically, a physiological feedback loop between the brain and immune systems, notably involving cytokines, have been identified, thus permitting an analysis of how pathogens may come to potently alter brain function. Such changes may affect adaptive and abnormal behaviors.

This book examines the nature of these relationships. Key topics include: basic mechanisms of neural-immune interactions; the effects of immunity on normal brain neurochemistry and behavioral processes; and how immune activity may contribute to clinical disorders such as schizophrenia, depression, aggression, pain and stress.

Download Link

Author(s) : Antonio Bayes de Luna and Miquel Fiol-Sala Publisher : Wiley-Blackwell Date       : 2008 Pages     : 344 Format    : PDF ISBN-10  : 1405173629

The ECG is a fundamental diagnostic tool in cardiology, allowing accurate diagnosis and monitoring of acute and chronic ischemic heart disease. In this most comprehensive book of its kind, internationally renowned authors correlate electrocardiographic recordings with anatomical patterns of myocardial ischemia to improve the diagnosis and management of patients with ischemic heart disease.

The book is structured in two sections. Part One covers electrocardiographic patterns of ischemia, injury and infarction.
* Each chapter discusses a different ECG abnormality in turn, clearly explaining the ischemic insults and electrophysiological mechanisms underlying each pattern to promote rapid and accurate interpretation of the ECG in the clinical setting.
* ECG abnormalities are correlated with myocardial anatomy and coronary angiography to produce a series of practical diagnostic algorithms that allow the clinician to identify not only the occluded artery but the precise location of the occlusion within the artery, facilitating appropriate therapeutic decisions.
* The authors also propose a new classification of Q-wave myocardial infarctions based on imaging correlations with advanced techniques such as contrast-enhanced cardiac magnetic resonance.

Download Link